Publications

Google Scholar link

Richardson-Matthews, R., Velko, K., Bhunia, B., Ghosh, S., Oktawiec, J., Brunzelle, J. S., Dang, V.T., Nguyen, A.I., 2025, J. Am. Chem. Soc. ASAP

Pre-print on ChemRxiv

25. “Advances in the design of π-conjugated peptide assemblies"

Nguyen, A.I.*, Ganatra, P., Hess, S.S., Nichols, S., Heinz-Kunert, S.L., 2025, Trends Chem. In Press.

24. “Diverse proteomimetic frameworks via rational design of π-stacking peptide tectons"

Ganatra, P., Wang, D. F., Ganatra, V., Dang, V.T., Nguyen, A.I., J. Am. Chem. Soc. 2024, 146, 22236–22246

23. “Crystallography reveals metal-triggered restructuring of β-hairpins"

Dang, V.T., Engineer, A., McElheny, D., Drena, A., Telser, J., Tomczak, K., Nguyen, A.I., Chem. Eur. J. 2024, e202402101

Pre-print on ChemRxiv (May 22, 2024)

22. “Peptide hydrogen-bonded organic frameworks"

Vijayakanth, T.*, Dasgupta, S., Ganatra, P., Rencus-Lazar, S., Desai, A. V., Nandi, S., Jain, R., Bera, S., Nguyen, A. I.*, Gazit, E.*, Misra, R.* Chem. Soc. Rev., 2024, 53, 3640-3655.

21. “Pore restructuring of peptide frameworks by mutations at distal packing residues"

Heinz-Kunert, S. L., Pandya, A., Dang, V. T., Oktawiec, J., Nguyen, A. I. Biomacromolecules, 2024, 25, 2016-2023

20. Noncovalent peptide assembly enables crystalline, permutable, and reactive thiol frameworks

Hess, S.S., Coppola, F., Dang, V. T., Tran, P. T., Mickel, P. J., Oktawiec, J., Ren, Z., Král, P., Nguyen, A. I.,

J. Am. Chem. Soc. 2023, 145, 19588-196000.

19. Peptidic scaffolds enable rapid and multivariate secondary sphere evolution for an abiotic metallocatalyst

Ghosh, S., Tran, P. N., McElheny, D., Perez, J. J., Nguyen, A. I. Inorg. Chem. 2022, 61, 6679–6687

18. Assembly of π-Stacking Helical Peptides into a Porous and Multivariable Proteomimetic Framework

Heinz-Kunert, S. L.‡, Pandya, A.‡, Dang, V. T., Tran, P. N., Ghosh, S., McElheny, D., Santarsiero, B. D., Ren, Z., Nguyen, A. I., J. Am. Chem. Soc., 2022, 144, 7001–7009. DOI: 10.1021/jacs.2c02146. ‡Equal Contribution

Highlighted by Nature Chemistry

Prior to UIC

17. "Mechanistic Aspects of Cobalt-Oxo Cubane Clusters in Oxidation Chemistry"

Amtawong, J., Nguyen, A. I., Tilley, T. D., J. Am. Chem. Soc., 2022, 144, 1475-1492. DOI: 10.1021/jacs.1c11445

16. "DNA Origami Protection and Molecular Interfacing through Engineered Sequence-Defined Peptoids"

Wang, S.-T.; Gray, M. A.; Xuan, S.; Lin, Y.; Byrnes, J.; Nguyen, A. I.; Todorova, N.; Stevens, M. M.; Bertozzi, C. R.; Zuckermann, R. N.; Gang, O.; Proc. Natl. Acad. Sci. USA. 2020, 117, 6339-6348.

15. "Cooperative Intramolecular Hydrogen-Bonding Strongly Enforces cis-Peptoid Folding"

Wijaya, A.,* Nguyen, A. I.,* Roe, L. T., Butterfoss, G. L., Spencer, R. K., Li, N. K., Zuckermann, R. N., J. Am. Chem. Soc., 2019, 141, 19436-19447. DOI: https://doi.org/10.1021/jacs.9b10497

*Equal contribution

Highlighted in JACS Spotlights

14. "Isolation and Study of Ruthenium–Cobalt Oxo Cubanes Bearing a High-Valent, Terminal Ru(V)–Oxo with Significant Oxyl Radical Character"

Amtawong, J., Balcells, D., Wilcoxen, J., Handford, R. C., Biggins, N., Nguyen, A. I., Britt, R. D., Tilley, T. D., J. Am. Chem. Soc., 2019, 141, 19436-19447. DOI: 10.1021/jacs.9b10320

Highlighted in JACS Spotlights

13. “Stabilization of reactive Co4O4 cubane oxygen-evolution catalysts within porous frameworks”

Nguyen, A. I.,* Van Allsburg, K. M.,* Terban, M. W., Bajdich, M., Oktawiec, J., Amtawong, J., Ziegler, M. S., Dombrowski, J. P., Lakshmi, K. V., Drisdell, W. S., Yano, J., Billinge, S. J. L., Tilley, T. D. Proc. Natl. Acad. Sci. U. S. A., 2019, 116, 11630-11639. *Equal contribution

Commentary by Wang, D. and Meyer, T. J.

Media coverage in: UC Berkeley, Berkeley Lab, AAS, DOE, phys.org

12. “A Bio-Inspired Approach to Ligand Design: Folding Single-Chain Peptoid to Chelate a Multimetallic Cluster”

Nguyen, A. I.; Spencer, R. K.; Anderson, C. L.; Zuckermann, R. N. Chem. Sci., 2018, 9, 8806-8813.

11. “Influence of a “Dangling” Co(II) Ion Bound to a [MnCo3O4] Oxo Cubane”

Nguyen, A. I.; Darago, L. E.; Balcells, D.; Tilley, T. D. J. Am. Chem. Soc., 2018, 140, 9030-9033.

10. “Sequence-Dependent Self-Assembly and Structural Diversity of Islet Amyloid Polypeptide-Derived β-Sheet Fibrils”

Wang, S–T.; Lin, Y.; Spencer, R. K.; Thomas, M. R.; Nguyen, A. I.; Amdursky, N.; Pashuck, E. T.; Skaalure, S. C.; Song, C. Y.; Parmar, P. A.; Morgan, R. M.; Ercius, P.; Aloni, S.; Zuckermann, R. N.; Stevens, M. M. ACS Nano, 2017, 11, 8579–8589.

9. “Artificial Metalloproteins Containing Co4O4 Active Sites”

Olshansky, L.; Huerta-Lavorie, R.; Nguyen, A. I.; Vallapurackal, J.; Furst, A.; Tilley, T. D.; Borovik, A. S. J. Am. Chem. Soc. 2018, 140, 2739-2742.

8. "Manganese–Cobalt Oxido Cubanes Relevant to Manganese-Doped Water Oxidation Catalysts”

Nguyen, A. I.; Suess, D. L. M.; Darago, L. E.; Oyala, P. H.; Levine, D. S.; Ziegler, M. S.; Britt, R. D.; Tilley, T. D. J. Am. Chem. Soc. 2017, 139, 5579-5587.

7. “Synthetic control and empirical prediction of redox potentials for Co4O4 cubanes over a 1.4 V range: implications for catalyst design and evaluation of high-valent intermediates in water oxidation”

Nguyen, A. I.; Wang, J.; Levine, D. S.; Ziegler, M. S.; Tilley, T. D. Chem. Sci. 2017, 8, 4274-4284.

6. “Mechanistic Investigations of Water Oxidation by a Molecular Cobalt Oxide Analogue: Evidence for a Highly Oxidized Intermediate and Exclusive Terminal Oxo Participation”

Nguyen, A. I.; Ziegler, M. S.; Oña-Burgos, P.; Sturzbecher-Hohne, M.; Kim, W.; Bellone, D. E.; Tilley, T. D. J. Am. Chem. Soc., 2015, 137, 12865-12872.

5. “Efficient C–H Bond Activations via O2 cleavage by a Dianionic Co(II) Complex”

Nguyen, A. I.; Hadt, R. G.; Solomon, E. I.; Tilley, T. D. Chem. Sci. 2014, 5, 2874-2878.

4. “Designing Catalysts for Nitrene Transfer Using Early Transition Metals and Redox-Active Ligands”

Heyduk, A. F.; Zarkesh, R. A.; Nguyen, A. I. Inorg. Chem. 2011, 50, 9849-9863.

3. “Catalytic Nitrene Transfer by a Zirconium(IV) Redox-Active Ligand Complex”

Nguyen, A. I.; Zarkesh, R. A.; Lacy, D. C.; Thorson, M. K.; Heyduk, A. F. Chem. Sci., 2011, 2, 166-169.

2. "N-tert-butyl ortho-aminophenol, ortho-iminoquinone, and a zirconium(IV) bis(aminophenol) complex”

Blackmore, K. J.; Nguyen, A. I.; Heyduk, A. F. Inorg. Synth., 2010, 35, 92-96.

1. “One- and Two- Electron Reactivity of a Tantalum(V) Complex with a Redox-Active Tris(amido) Ligand”

Nguyen, A. I.; Blackmore, K. J.; Carter, S. M.; Zarkesh, R. A.; Heyduk, A. F. J. Am. Chem. Soc., 2009, 131, 3307-3316.